NASDAQ$BBIO

Bridgebio Pharma Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

BridgeBio reported Q4 2025 revenue of $154.2M, driven by Attruby net product revenue of $146.0M.

Q4 revenues, net, were $154.2 million (Attruby $146.0M). Net loss $194.6 million on R&D and pipeline investment. Positive Phase 3 readouts for infigratinib and BBP-418; 7,804 Attruby prescriptions through Feb 2026.

  • Q4 revenue $154.2M; Attruby $146.0M.
  • Net loss $194.6M on pipeline spend.
  • FY revenue $502.1M.
  • Multiple Phase 3 wins in quarter.

Headline financials

Total Revenue

$154M

Previous: $5.88M+2521.6%
EPS (adj)

-$1.00

Previous: -$1.40+28.6%
Unique Patient Prescriptions

7.8K

No prior period
Unique Prescribers

1.9K

No prior period
TTR Stabilization

90.0%

No prior period
R&D Expense

$116M

No prior period
Net Income

-$195M

Previous: -$265M+26.6%
Operating Income

-$140M

Previous: -$226M+38.3%

Revenue & EPS history

Bridgebio · Revenue · Quarterly

$154M

Q4 2025+2,521.6%vs Q4 2024
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Revenue by segment

Bridgebio · $100K total across 1 segment · Q2 2023

  • License and Services Revenue
    $100K

Forward guidance

NDA submissions planned 1H 2026 for achondroplasia and LGMD programs; Attruby uptake accelerating.

Tailwinds

  • Attruby prescriber base expanding.
  • Phase 3 successes de-risk pipeline.
  • Commercial infrastructure scaling.

Headwinds

  • Large quarterly net loss.
  • Binary regulatory outcomes ahead.
  • Single-product concentration near term.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+1.5%

Avg return

Earnings day

+0.6%

Avg return

5 days after

+4.3%

Avg return

30 days after

48%

13 / 27 earnings

Positive

+40.9%

Q2 2022

Best reaction

-21.9%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-1.0%-3.2%-0.7%
Q4 2025-2.8%-4.1%+2.0%
Q3 2025-4.9%-7.9%+8.1%
Q1 2025+5.3%+4.9%-6.0%
Q4 2024+1.4%-5.3%-4.2%
Q3 2024-5.1%-9.2%+5.9%
Q2 2024+0.9%-4.2%+7.3%
Q1 2024+3.0%+2.8%+3.6%
Q4 2023-0.5%+4.6%-13.4%
Q3 2023+8.2%+10.3%+16.1%
Q2 2023-2.3%+0.8%-4.4%
Q1 2023-5.0%-4.4%-1.0%
Q4 2022-4.7%-6.6%+21.8%
Q3 2022-1.1%-7.0%-4.8%
Q2 2022+40.9%+39.7%+26.7%
Q1 2022-21.9%-29.5%-15.9%
Q4 2021+7.6%+13.9%+41.1%
Q3 2021+6.8%+2.0%-22.8%
Q2 2021+2.4%-1.1%-2.3%
Q1 2021-9.3%-7.2%+9.5%
Q4 2020+4.9%-1.8%-9.8%
Q3 2020-1.6%+0.3%+30.4%
Q2 2020+1.4%+0.2%+16.2%
Q1 2020-6.8%+6.1%-12.7%
Q4 2019+2.2%-9.3%-21.3%
Q3 2019+22.1%+26.2%+49.0%
Q2 2019+0.0%+4.8%-3.2%
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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