NASDAQ$ADAPY
Adaptimmune Therapeutics Plc · Q4 2021 earnings
Q4 2021 earnings · · Investor relations
Briefing
Adaptimmune reported financial results for the fourth quarter and full year ended December 31, 2021, and provided a business update.
Adaptimmune reported fourth quarter revenue of $1.4 million and is focused on filing its first BLA, building its MAGE-A4 franchise, scaling up its manufacturing capabilities, and making progress with its allogeneic platform in 2022. The company's cash, cash equivalents and marketable securities are expected to fund operations into early 2024.
- SPEARHEAD-1 met its primary endpoint - planning for afami-cel BLA submission in Q4 2022 for people with synovial sarcoma
- Moving to late-phase development with ADP-A2M4CD8: SURPASS-2 initiated in esophageal and EGJ cancers; initiating SURPASS-3 in ovarian cancer in 2022
- Allogeneic platform on-track for planned IND submission in 2023 for first product targeting MAGE-A4
- Started our strategic collaboration for allogeneic T-cell therapies with Genentech - $150 million upfront payment received
Headline financials
Revenue & EPS history
Adaptimmune · Revenue · Quarterly
$1.42M
Revenue by segment
Adaptimmune · $1.42M total across 1 segment · Q4 2021
- Development revenue$1.42M—100.0%
Forward guidance
The Company believes that its existing cash, cash equivalents and marketable securities, together with the upfront and additional payments under the Strategic Collaboration and License Agreement with Genentech, will fund the Company’s current operations into early 2024.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 18 quarterly earnings reports · overlaid with Q4 2021
-3.0%
Avg return
Earnings day
-7.9%
Avg return
5 days after
-3.2%
Avg return
30 days after
37%
16 / 43 earnings
Positive
+26.5%
Q3 2022
Best reaction
-37.7%
Q4 2024
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q3 2026 | +0.0% | -90.0% | — | |
| Q3 2025 | +0.0% | -90.0% | — | |
| Q2 2025 | +1.3% | -9.1% | -27.3% | |
| Q1 2025 | +4.7% | +0.7% | -7.9% | |
| Q4 2024 | -37.7% | -44.3% | -47.0% | |
| Q3 2024 | -25.5% | +12.5% | -1.9% | |
| Q2 2024 | +5.8% | +8.8% | +8.8% | |
| Q1 2024 | +4.3% | -4.3% | -12.2% | |
| Q4 2023 | +19.2% | +5.5% | -6.2% | |
| Q3 2023 | -8.2% | -20.6% | -8.6% | |
| Q2 2023 | -5.2% | -8.7% | -14.5% | |
| Q1 2023 | +2.2% | -1.5% | -27.4% | |
| Q4 2022 | -29.0% | -36.4% | -40.3% | |
| Q3 2022 | +26.5% | +51.2% | +6.0% | |
| Q2 2022 | +20.6% | +14.4% | +4.1% | |
| Q1 2022 | -8.8% | -17.5% | -0.6% | |
| Q4 2021 | -4.9% | +19.8% | +7.7% | |
| Q3 2021 | +0.0% | +0.7% | -34.6% | |
| Q2 2021 | +2.3% | +14.3% | +79.1% | |
| Q1 2021 | -6.6% | -6.7% | -7.4% | |
| Q4 2020 | -7.5% | -9.3% | -14.4% | |
| Q3 2020 | -1.7% | -7.9% | -15.7% | |
| Q2 2020 | -8.5% | -6.8% | -8.9% | |
| Q1 2020 | +2.4% | +13.9% | +118.9% | |
| Q4 2019 | +3.1% | -0.3% | -18.8% | |
| Q3 2019 | -18.2% | -25.6% | +1.8% | |
| Q2 2019 | -23.7% | -36.0% | -51.1% | |
| Q1 2019 | -6.9% | -9.1% | -18.1% | |
| Q4 2018 | -9.7% | -12.1% | -11.5% | |
| Q3 2018 | -6.7% | -13.3% | -19.4% | |
| Q2 2018 | -8.7% | -8.3% | +19.0% | |
| Q1 2018 | +2.6% | -0.5% | -1.2% | |
| Q4 2017 | +20.1% | +12.5% | +35.2% | |
| Q3 2017 | +8.8% | +8.8% | +7.9% | |
| Q2 2017 | +1.7% | +2.4% | +23.2% | |
| Q1 2017 | -3.0% | +4.1% | +0.6% | |
| Q3 2016 | +2.9% | +0.0% | -14.6% | |
| Q2 2016 | -7.2% | -12.6% | -16.9% | |
| Q1 2016 | -5.1% | — | — | |
| Q3 2015 | -10.5% | — | — | |
| Q4 2015 | -10.5% | — | — | |
| Q1 2015 | -0.8% | — | — | |
| Q2 2015 | -0.8% | — | — | |
| Q4 2014 | — | — | — | |
| Q3 2014 | — | — | — | |
| Q2 2014 | — | — | — | |
| Q1 2014 | — | — | — | |
| Q4 2013 | — | — | — | |
| Q3 2013 | — | — | — |
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