NASDAQ$ACET

Adicet Bio Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Adicet Bio reported financial results for Q4 2023 and full year, highlighting progress in clinical pipeline expansion into autoimmune diseases and advancements in ADI-001 and ADI-270 development.

Adicet Bio reported a net loss of $29.5 million for the fourth quarter of 2023, with R&D expenses at $24.8 million and G&A expenses at $6.8 million. The company highlighted the FDA clearance for ADI-001 in lupus nephritis and progress in advancing ADI-270 preclinical development. They extended their projected cash runway into 2H 2026.

  • FDA cleared IND application for ADI-001 in lupus nephritis, with Phase 1 study initiation expected in 2Q 2024.
  • Advanced ADI-270 preclinical development in solid tumors, remaining on track to file IND in renal cell carcinoma in 2Q 2024.
  • Presented persistence and pharmacodynamic data from ADI-001 Phase 1 study at ASH Annual Meeting.
  • Extended projected cash runway into the second half of 2026 following a successful capital raise and ATM program.

Headline financials

Total Revenue

$12.9M

Previous: -$25M+151.6%
EPS (adj)

-$0.69

Previous: -$0.72+4.2%
Weighted-average shares used in net loss per share

43.0M

No prior period
Research and development expenses

$24.8M

No prior period
General and administrative expenses

$6.81M

No prior period
Interest income

$2.18M

No prior period
Other expense, net

-$101K

No prior period
Capital Expenditures

-$136K

Previous: $6.49M-102.1%
Net Income

-$29.5M

Previous: -$29.9M+1.3%
Operating Income

-$31.6M

Previous: -$31.6M-0.0%
Gross Profit

$11.2M

No prior period
R&D Expense

$24.8M

No prior period
Stock-Based Comp

$4.91M

Previous: $4.25M+15.6%

Revenue & EPS history

Adicet Bio · Revenue · Quarterly

$12.9M

Q4 2023-151.6%vs Q4 2022
Beat estimate in 2 of 10 quarters(20%)
ActualEstimate

Forward guidance

Adicet Bio anticipates several milestones, including initiating a Phase 1 study for ADI-001 in lupus nephritis in 2Q 2024 and filing an IND for ADI-270 in renal cell carcinoma in 2Q 2024. Preliminary clinical data for ADI-001 in lupus nephritis is expected in Q4 2024 or Q1 2025.

Tailwinds

  • Initiate Phase 1 study of ADI-001 in lupus nephritis in 2Q 2024.
  • File IND for ADI-270 in renal cell carcinoma in 2Q 2024.
  • Provide clinical update on ADI-001 in MCL patients in the second half of 2024.
  • Provide clinical data from Phase 1 study of ADI-270 in the first half of 2025.
  • Expand ADI-001 development into additional autoimmune indications.

Headwinds

  • Clinical data timelines are subject to study site activation progression and patient enrollment.
  • IND clearance in additional autoimmune indications is required.
  • Regulatory clearance is needed for ADI-270 Phase 1 study.
  • Timelines are subject to study initiation progress.
  • Future results may not be predictive of ongoing studies.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+1.1%

Avg return

Earnings day

+1.2%

Avg return

5 days after

-5.0%

Avg return

30 days after

52%

16 / 31 earnings

Positive

+29.7%

Q4 2021

Best reaction

-9.1%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.4%-5.3%+1.4%
Q4 2025-3.2%-1.6%-4.0%
Q3 2025-3.6%-6.4%-22.6%
Q1 2025-6.9%-7.5%-7.9%
Q4 2024-2.3%+15.0%-33.8%
Q3 2024+1.5%-3.8%-19.8%
Q2 2024+7.9%+20.5%+20.5%
Q1 2024-2.8%+11.1%+0.7%
Q4 2023+9.7%+12.3%+3.8%
Q3 2023-4.9%-10.3%+4.9%
Q2 2023+6.8%-2.7%-23.2%
Q1 2023+4.1%-4.5%-14.9%
Q4 2022-3.1%-19.5%-29.5%
Q3 2022+1.9%+11.0%+3.8%
Q2 2022-9.1%-11.0%-4.9%
Q1 2022+8.6%+13.1%+9.6%
Q4 2021+29.7%+31.0%+37.6%
Q3 2021+3.2%+0.8%+49.7%
Q2 2021+8.1%-5.9%+6.4%
Q1 2021+1.5%+7.7%-22.5%
Q4 2020-0.7%+6.2%-11.2%
Q3 2020+5.9%+9.2%+22.3%
Q2 2020+0.4%+4.4%-17.3%
Q1 2020+9.1%+10.3%+24.6%
Q4 2019-8.5%-17.1%-6.0%
Q3 2019-5.3%+6.7%-85.2%
Q2 2019-3.5%-3.7%-22.2%
Q1 2019-4.6%-7.3%+1.3%
Q4 2018-8.3%-10.8%-23.3%
Q3 2018-5.8%-5.2%-2.7%
Q2 2018+5.1%-0.9%+9.3%
Q1 2018
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Q1 2017
Q4 2016
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Q2 2016
Q1 2016
Q4 2015
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Q1 2014
Q4 2013
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Q4 2012
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Q1 2012
Q4 2011
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Q1 2011
Q4 2010
Q3 2010
Q2 2010
Q1 2010

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