EURONEXT-BRU$ARGX

Argenx Se · Q1 2025 earnings

Q1 2025 earnings · · Investor relations

Briefing

argenx Q2 VYVGART sales hit $949M as company turns profitable with EPS of $4.02

argenx SE reported second-quarter 2025 global product net sales of $949 million, up 97% operationally year over year and 19% sequentially, driven by VYVGART growth across myasthenia gravis and CIDP indications. Total operating income was $967 million and operating profit was $201 million versus an operating loss of $45 million in Q2 2024. Net income was $245 million with basic EPS of $4.02 (diluted $3.74). For the first half, product net sales reached $1.74 billion and net income was $415 million. The VYVGART SC prefilled syringe is approved in the U.S. and EU, with more than 2,500 CIDP patients on treatment globally. R&D spending remained elevated at $328 million in Q2 as the company advances registrational and proof-of-concept programs across efgartigimod, empasiprubart, and ARGX-119 toward Vision 2030 targets.

  • Q2 product net sales $949M (+97% operational YoY; +19% vs Q1)
  • Q2 operating profit $201M vs $(45)M loss; net income $245M
  • Basic EPS $4.02 (diluted $3.74) in Q2; H1 product sales $1.74B
  • VYVGART SC prefilled syringe launched; 2,500+ CIDP patients on treatment globally
  • ARGX-119 advancing to registrational CMS study; multiple H2 2025 pipeline readouts expected

Headline financials

Total Revenue

$949M

Previous: $398M+138.2%
EPS (adj)

$4.02

Previous: -$1.04+486.5%
Product Net Sales

$949M

No prior period
Operational Sales Growth (YoY)

97.0%

No prior period
CIDP Patients on Treatment Globally

2.5K

No prior period
R&D Expense

$328M

No prior period
Net Income

$245M

No prior period
Operating Income

$201M

No prior period

Revenue & EPS history

Argenx · Revenue · Quarterly

$949M

Q1 2025+138.2%vs Q1 2024
Beat estimate in 10 of 14 quarters(71%)
ActualEstimate

Revenue by segment

Argenx · $1.52B total across 1 segment · Q2 2026

  • VYVGART
    $1.52B—

Forward guidance

argenx targets Vision 2030 with 50,000 patients treated globally, 10 labeled indications, and five Phase 3 pipeline candidates by 2030, with six registrational and six proof-of-concept readouts expected by end of 2026.

Tailwinds

  • VYVGART remains fastest-growing biologic in MG with early-stage CIDP launch momentum
  • Multiple near-term readouts including seronegative gMG, DGF, and ARGX-109 Phase 1

Headwinds

  • SG&A expenses rose to $325M in Q2 on global commercial expansion
  • Heavy R&D investment continues with $637M spent in H1

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.3%

Avg return

Earnings day

-0.1%

Avg return

5 days after

+3.8%

Avg return

30 days after

56%

18 / 32 earnings

Positive

+11.2%

Q4 2017

Best reaction

-9.1%

Q1 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026———
Q4 2026+1.7%-8.1%-19.0%
Q1 2025-9.1%-12.9%-5.9%
Q4 2024+0.3%-0.3%-5.4%
Q3 2024+8.0%+9.2%+11.8%
Q2 2024+6.5%+9.7%+11.3%
Q1 2024-3.0%-7.8%-2.7%
Q3 2023+6.6%+7.7%-2.9%
Q2 2023-1.1%-3.3%-2.7%
Q1 2023+3.0%+2.4%+0.9%
Q4 2022-5.9%-8.1%+1.0%
Q3 2022+1.4%-1.1%-2.6%
Q2 2022+1.8%-0.0%+7.3%
Q1 2022+8.0%+2.2%+8.0%
Q4 2021-8.7%-9.5%+11.7%
Q3 2021+8.0%+14.8%-1.2%
Q2 2021-1.0%+1.3%+9.5%
Q1 2021+6.3%+0.8%+20.4%
Q4 2020-8.4%-0.3%-10.7%
Q3 2020-2.5%+0.8%+4.9%
Q2 2020-7.8%-7.2%-8.2%
Q1 2020+5.7%+10.0%+45.0%
Q4 2019-6.1%-2.1%-13.2%
Q3 2019+0.4%+4.9%+24.8%
Q2 2019+1.5%-4.4%-6.4%
Q1 2019-3.2%-6.2%-3.0%
Q4 2018+0.4%-2.3%-6.9%
Q3 2018-5.0%-3.9%+17.2%
Q2 2018-1.2%-0.9%+1.8%
Q1 2018+2.6%+3.5%+13.2%
Q4 2017+11.2%+7.7%+5.0%
Q3 2017+1.1%+0.7%+13.4%
Q2 2017-0.6%-0.6%+4.2%
Q1 2017———
Q4 2016———
Q3 2016———
Q2 2016———
Q1 2016———
Q4 2015———
Q3 2015———
Q2 2015———
Q1 2015———
Q4 2014———
Q3 2014———
Q2 2014———
Q1 2014———
Q4 2013———
Q3 2013———
Q2 2013———
Q1 2013———

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